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Pineal germinoma

Pineal organ is a small endocrine organ present in the vertebrate brain also known as the third eye. It produces a hormone known as melatonin which regulates the sleep-wake cycle as well as seasonal functions of vertebrates. Melatonin is a serotonin subordinate. It is a reddish-dim substance resembling a minor pine cone fit as a fiddle. It is found rostro-dorsal to the superior colliculus just behind and underneath the striamedullaris, between the thalamic bodies. Pineal organ is a piece of epithalamus. It is a calcified part of brain that can be easily seen in plain X-beam. In people it is comprised of a lobular parenchyma of pinealocytes surrounded by connective tissue spaces. The organ’s surface is secured by a pial capsule. Pinealocytes structure the greatest main part of this organ yet different types of cells are also present that contrast in their cellular details.




Five types of cells that vary in their cellular structures are found in the pineal organ. Pinealocytes are the most bottomless cells of the third eye. They are comprised of a cell body with 4-5 developing processes and can be stained by special silver impregnation methods. They secrete melatonin. The cytoplasm is softly basophilic and shows protracted and stretched cytoplasmic processes that reach out to the connective tissue septa. By pinealocytes are the interstitial cells that are situated in the middle of them. They have prolonged cores and their cytoplasm takes darker stain when contrasted with the pinealocytes. The organ is traversed by numerous capillaries which contain perivascular phagocytes. These perivascular phagocytes are antigen presenting cells. In higher vertebrates neurons are also present in the organ however they are absent in rodents. In some species neuron-like peptidergic cells are also present and it is trusted that they have a paracrine administrative part.




Superior cervical ganglion sends sympathetic nerve supply to the pineal organ yet sphenopalatine and otic ganglia also supply parasympathetic nerves to it. Neurons of the trigeminal ganglia at long last innervate the organ with nerve fibers containing a neuropeptide, PACAP. Human follicles have a variable measure of an abrasive material known as coporaarenacea which is synthetically comprised of calcium phosphate, calcium carbonate, magnesium phosphate and ammonium phosphate. Studies completed in 2002 uncover that calcium carbonate is present as calcite. Calcium, phosphorous and fluoride deposits present in the pineal organ assume some part in maturing.


Germinoma is a specific sort of germ cell based tumor. Individuals that have these types of tumors may find that they are malignant, yet there are numerous that are considered to be kindhearted as well. Historically, the term was used to describe a tumor that was situated in the brain area that had the same characteristics as two distinctive tumors that are regularly discovered in the ovaries in a female and the testes of a male.




There are numerous symptoms associated with germinoma. As with all tumors, the symptoms that are experienced by every patient will be needy upon the definite area of the development, as well as the general size of the tumor. The symptoms will also be needy upon the rate in which the tumor is developing.